भाषा:

Cold nights, closed curtains and ammonia make winter the season of CRD, E. coli, IB, Ranikhet, ascites and kidney trouble in broilers. Many farmers react by buying whatever the shop suggests on the day a problem shows up. A fixed plan works better: you know on day 1 what goes into the water on every day of the batch, what it is for, and roughly what it will cost. This page gives you exactly that, the official IMN Pyrophos 42-Day Winter Broiler Preventive Medicine Schedule for Winter 2026, made for farmers with EC (environment-controlled) sheds, followed by the reason behind every product in it.

In short: the schedule costs about ₹4,860 per 1,000 birds for the full 42 days, about ₹4.9 per chick (vaccine cost extra). It has the ND-IB vaccine on day 4, six plain-water days, and no antibiotics. Antibiotics stay what they should be: a vet’s decision when a bacterial disease is diagnosed.

Important: this is a preventive programme for a healthy flock. If birds are sick, call your vet first; supportive products do not replace diagnosis and treatment. Vaccine strains and the days for Gumboro and LaSota depend on your hatchery, your area and your vet. Always ask the hatchery which vaccines the chicks already got.

POULTRY

Grotek

Grotek

Wazan aur badhwar

500 g ₹679₹940

Order karein

POULTRY

Nexamune

Nexamune

Immunity booster

1 L ₹644₹1,190

Order karein
Grotek

POULTRY

Grotek

Wazan aur badhwar

500 g ₹679₹940

Order karein

How to read this table

  • All quantities are per 1,000 birds. Scale them for your flock: 5,000 birds = 5 times the quantity, 2,500 birds = 2.5 times.
  • First water (Entry 1) is the first water of the day, given in the morning. Next water (Entry 2) is the water you give after the first one is finished.
  • Dissolve each day’s quantity in the amount of water the birds finish in 3–4 hours in winter. Measure it: note how much the flock drank in the first 3–4 hours yesterday.
  • Where two products are joined with “+”, they go in the same water, as the schedule shows. Do not add other products of your own.
  • Never mix any product in vaccine water. On day 4 the first water is the ND-IB vaccine only; Alceau goes in the next water.
  • Plain-water days (day 23, 31, 35, 37, 39 and 40) are on purpose: they give the gut and the kidneys a rest. Give clean drinking water only.
  • In winter, water from an overhead tank can be very cold at dawn. Let it come to shed temperature before chicks drink it; cold water cuts drinking and chills the chicks.

IMN Pyrophos winter 2026 broiler medicine schedule: day 1 to 42

Quantities per 1,000 birds. Cost is the approximate cost of the products for that day, in rupees per 1,000 birds.

DayFirst water (Entry 1)Next water (Entry 2)Cost ₹/1,000 birds
Week 1 (day 1–7): arrival, ND-IB vaccine, early protection₹488
1Easy Brood 70 g (as soon as chicks arrive)Vitaden H 30 ml₹111
2Easy Brood 70 gAlceau 15 g₹101
3Pyrocal B 40 mlAlceau 15 g₹41
4ND-IB vaccine only (no product in vaccine water)Alceau 15 g₹22
5Vitaden H 35 mlPyrocal B 45 ml₹59
6Sel-E Boost 25 g + Nexamune 20 mlPyrocal B 50 ml₹62
7Sel-E Boost 25 g + Nexamune 20 mlVitaden H 50 ml₹92
Week 2 (day 8–14): kidney, liver, gut, immunity₹775
8Nephrowin 50 mlHepasol DS 50 ml₹51
9Nephrowin 50 ml + Grotek 30 gHepasol DS 50 ml₹92
10Remipro 25 g + Grotek 30 gVitaden H 50 ml₹126
11Septima 70 gPyrocal B 60 ml₹139
12Septima 70 gAscitox Q10 90 g₹174
13Hepasol DS 50 mlAscitox Q10 90 g + Sel-E Boost 35 g₹124
14Pyrocal B 70 mlSel-E Boost 35 g₹69
Week 3 (day 15–21): fast growth, breathing, ascites watch₹1,297
15Pyrocal B 70 mlRemipro 50 g₹95
16Respoze 50 mlNexamune 50 ml₹78
17Respoze 50 mlVitaden H 75 ml₹126
18Hepasol DS 100 mlGrotek 100 g₹187
19Septima 120 gGoutster 80 g₹266
20Septima 120 gGrotek 80 g₹299
21Alceau 100 gAscitox Q10 140 g₹246
Week 4 (day 22–28): ascites, kidney, liver₹829
22Ascitox Q10 140 g–₹98
23Plain water (no product)–₹0
24Respoze 100 mlGrotek 80 g₹201
25Goutster 100 g–₹94
26Hepasol DS 120 ml–₹62
27Septima 150 g–₹238
28Grotek 100 g–₹136
Week 5 (day 29–35): weight and gut₹839
29Remipro 150 gGrotek 100 g₹324
30Ascitox Q10 180 g–₹126
31Plain water (no product)–₹0
32Nexamune 120 mlHepasol DS 120 ml₹139
33Remipro 150 g–₹188
34Hepasol DS 120 ml–₹62
35Plain water (no product)–₹0
Week 6 (day 36–42): finishing₹631
36Ascitox Q10 200 g–₹140
37Plain water (no product)–₹0
38Grotek 120 g–₹163
39Plain water (no product)–₹0
40Plain water (no product)–₹0
41Remipro 150 g–₹188
42Ascitox Q10 200 g–₹140
Total day 1–42: about ₹4,860 per 1,000 birds (about ₹4.9 per chick); vaccine extra≈ ₹4,860

Scroll the table sideways on mobile. Total of the daily costs: ₹4,859, so about ₹4,860 per 1,000 birds, or about ₹4.9 per chick for 42 days. Vaccine cost is extra.

Download this schedule as a 1-page PDF to print and pin in the shed, or share with your supervisor on WhatsApp.
⬇ Download PDF (free) Or ask on WhatsApp

Why each product is in the schedule

Every product has a job at a certain age. Click a name to see the full product page.

Easy Brood (day 1–2, first water)

A start-up supplement for chicks with electrolytes, osmolytes, glucose for energy, vitamins, amino acids and probiotics. It replaces jaggery, sugar or salt water, whose sucrose feeds gut bacteria that can infect the yolk sac. It reduces transport stress and dehydration, helps early navel healing and lowers the chance of yolk sac infection. Prepare the solution before the chicks arrive and give it as soon as they reach the shed.

Easy Brood chick start-up supplement by IMN Pyrophos

Day 1–2 · in place of jaggery water

Easy Brood

Start-up solution for chicks: electrolytes, osmolytes, glucose for energy, vitamins C and B, betaine, glycine and probiotics. Reduces transport stress and dehydration, helps early navel healing, lowers the chance of yolk sac infection and early mortality. No need for jaggery, sugar or salt solutions. Antibiotic free. 250 g pack ₹295.

Dose: in the IMN winter schedule, 70 g per 1,000 chicks in the first water on day 1 (as soon as chicks arrive) and day 2. Label: 3–4 g per litre of drinking water, i.e. 50–70 g per 1,000 chicks per day. Prepare the solution before the chicks arrive.

500 g ₹565MRP ₹898

Vitaden H (day 1, 5, 7, 10, 17)

A multivitamin with seven vitamins: A, E, D3, B12, C, biotin and niacin. In the schedule it comes on arrival day, around the vaccine (day 5 and 7) and in the fast-growth weeks (day 10 and 17), with the quantity going up as the birds grow.

Alceau (day 2–4 next water, day 21)

A herbal formula made from onion, garlic, tulsi and cinnamon extracts. It helps prevent early chick mortality in brooding (day 2 to 7) and helps yolk dissolution, which is why it sits in the next water on day 2, 3 and 4, including vaccine day after the vaccine water is finished. On day 21 a larger quantity helps against respiratory infections like CRD and secondary bacterial infections as winter pressure builds.

Pyrocal B (day 3, 5, 6, 11, 14, 15)

Liquid calcium and phosphorus with B complex vitamins, iron and trace minerals, and an appetite stimulant. It reduces the chance of lameness, helps weight gain and helps bring uniformity in the flock, which is why it appears through the first two weeks of fast bone growth.

Sel-E Boost (day 6–7, 13–14)

Vitamin E and selenium, time-tested stress relievers that reduce oxidative stress. It reduces the chances of vaccination failure and is helpful during brooding, which is why it comes right after the day 4 ND-IB vaccine, together with Nexamune.

Nexamune (day 6–7, 16, 32)

Vitamin E, selenium, amla, tulsi and ashwagandha extracts, vitamin C, vitamin D and niacin: an antioxidant shield that supports immunity. On day 6–7 it supports immunity after the day 4 vaccine and reduces the chances of vaccination failure. The later doses support the immune system against outbreaks like Gumboro, IB and ND and reduce the severity of CRD and other respiratory problems.

Nexamune immune booster for poultry by IMN Pyrophos

Immunity and vaccination support

Nexamune

Vitamin E, selenium, amla, tulsi and ashwagandha extracts, vitamin C, vitamin D and niacin: an antioxidant shield that supports immunity. Helps reduce the chance of vaccination failure, supports the immune system in outbreaks like IB, ND, Gumboro, IBH and LPAI, and reduces the severity of CRD and other respiratory problems.

Dose: in the IMN winter schedule, per 1,000 birds: 20 ml on day 6 and 7, 50 ml on day 16, 120 ml on day 32. Label: 1 ml per litre of water or 15 ml per 100 birds for immunity and stress; 2 ml per litre before and after vaccination; 25–30 ml per 100 birds during viral outbreaks.

1 L ₹644MRP ₹1,190

Nephrowin (day 8–9)

A kidney flusher tonic. Poultry kidneys pass out uric acid, which does not dissolve well and can cause trouble on high-protein feed. Nephrowin helps flush uric acid and other toxins, helps prevent gout and reduces the chance of baby chick nephropathy, which is why it comes early, while chicks are on high-protein starter feed.

Hepasol DS (day 8, 9, 13, 18, 26, 32, 34)

A liver tonic with silymarin and liquorice extracts, choline chloride, B vitamins, liver and yeast extracts, methyl donors and methionine. It reduces fatty liver conditions, increases the liver’s detoxification power, increases feed intake and reduces FCR. Silymarin helps in toxicity, and feed stored in damp winter weather can carry toxins, so the liver gets regular support up to day 34.

Grotek (day 9, 10, 18, 20, 24, 28, 29, 38)

B group vitamins, minerals and herbal antioxidants. It improves feed intake and reduces FCR, increases growth rate so birds reach market weight earlier, supports the liver, and helps keep weight during infections and regain it after viral or CRD outbreaks. It is the most-used product in the schedule, because weight is what you sell.

Grotek weight gainer and growth promoter for broilers by IMN Pyrophos

Weight and growth

Grotek

B group vitamins, minerals and herbal antioxidants (amla, ashwagandha, tulsi). Improves feed intake and reduces FCR, increases growth rate to reach market weight early, supports the liver, and helps keep weight during infections and antibiotic use and regain it after viral or CRD outbreaks. Contains no iron.

Dose: in the IMN winter schedule, per 1,000 birds: 30 g on day 9 and 10, 80 g on day 20 and 24, 100 g on day 18, 28 and 29, 120 g on day 38. Label: 1–2 g per litre of water for 15–18 hours a day for 5 days; during or after infections 1 g per 5 kg body weight.

500 g ₹679MRP ₹940

Remipro (day 10, 15, 29, 33, 41)

A probiotic and prebiotic blend with antioxidants. It acts as a gut conditioner, restores normal gut flora, reduces loose droppings, improves digestion and FCR, and helps fight coccidiosis and necrotic enteritis, two problems that follow wet winter litter. The Septima page advises using Septima once before Remipro for better results against loose droppings, and the schedule follows that pattern: Septima on day 11–12, Remipro on day 15.

Septima (day 11–12, 19–20, 27)

A herbal combination (curcumin, ursolic acid, eugenol) for intestinal sepsis, which comes from poor feed, birds eating litter or contaminated water. Septima helps in sudden mortality from Clostridium, Salmonella and E. coli, works in necrotic enteritis and coccidiosis, and helps prevent loose droppings. In the schedule it is always the only product in the first water.

Ascitox Q10 (day 12, 13, 21, 22, 30, 36, 42)

A formula for managing ascites (water belly) in fast-growing broilers, especially in winter. It helps prevent metabolic ascites, reduces SDS (sudden death) mortality, reduces metabolic acidosis and supports the heart and lungs. Closed winter sheds mean less oxygen and more ammonia, and heavy birds in weeks 4–6 suffer most, so the quantity rises from 90 g to 200 g per 1,000 birds as the birds grow.

Ascitox Q10 for ascites prevention in broilers by IMN Pyrophos

Ascites and SDS prevention

Ascitox Q10

For the management of ascites in fast-growing broilers, especially in winter. Helps prevent metabolic ascites, helps control mortality, reduces SDS-related mortality and metabolic acidosis, and supports proper working of the heart and lungs.

Dose: in the IMN winter schedule, per 1,000 birds: 90 g on day 12 and 13, 140 g on day 21 and 22, 180 g on day 30, 200 g on day 36 and 42. If ascites starts (label): 3–4 g per litre of night-time drinking water for 3 to 5 days, holding feed while giving.

1 kg ₹698MRP ₹1,080

Respoze (day 16–17, 24)

A herbal solution for respiratory sounds in poultry, with ginger, tulsi, thyme and garlic extracts and camphor. Dust, ammonia and germs in closed winter sheds make thick mucus in the airway; Respoze helps thin the phlegm and open the airway. The schedule gives 50 ml per 1,000 birds on day 16 and 17 and 100 ml on day 24.

Goutster (day 19, 25)

An anti-gout combination. When the kidneys are overloaded, urates can settle in the kidneys and other organs and cause gout or kidney stones. Goutster increases water intake and kidney efficiency and helps dissolve uric acid so it is flushed out. Birds drink less in winter, which makes this kidney support useful.

Vaccination in this schedule

The IMN schedule fixes one vaccine day: ND-IB (Newcastle disease + infectious bronchitis) on day 4. The other common broiler vaccines depend on your hatchery, your area and your vet.

At the hatchery (day 0–1)

Many hatcheries give Marek’s vaccine, and some give an ND+IB spray or injection before the chicks leave. Practice differs between hatcheries. Ask for it in writing with the chick bill. If ND+IB was already given at the hatchery, your vet may change or skip the day 4 dose.

ND-IB live (day 4)

Protects against Ranikhet (Newcastle disease) and infectious bronchitis, the two big viral breathing diseases of winter. On day 4 the first water is vaccine water only, with nothing else in it. Alceau 15 g per 1,000 birds goes in the next water, after the vaccine water is finished. Read more about IB in poultry.

Gumboro (IBD) and ND LaSota booster

Gumboro damages the bursa, the organ that builds immunity in young chicks; its timing depends on the mother flock’s antibodies, so the day differs between hatcheries. Common windows are around day 12–14 for intermediate IBD and around day 18–24 for the LaSota booster, but follow your hatchery and vet. Some vets add a second IBD dose in areas with a history of Gumboro. On any vaccine day, the vaccine goes in the first water alone; give that day’s schedule products in the next water after the vaccine water is finished. If you are unsure how to fit a vaccine day into the chart, ask on WhatsApp.

Vaccine handling in winter: where most vaccines fail

A vaccine that is handled badly does not protect, even if it was given on the right day. Cold weather brings its own problems: birds drink less, and farmers are tempted to warm the water or add many products together.

Cold chain

  • Live freeze-dried vaccines must stay at 2–8 °C, from the shop to your fridge. Carry them in an ice box with ice packs, not loose in a pocket or a bag.
  • Do not let them freeze, and do not keep them in a fridge door that opens all day.
  • Check the expiry date and the batch number, and write them in your register.

Water vaccination step by step

  1. Stop chlorine, sanitisers and acidifiers in the water from the day before, and do not restart until the vaccine water is finished. Chlorinated water kills live vaccine. Never use chlorinated tap water to mix vaccine.
  2. Clean the drinkers with plain water only, no soap or disinfectant.
  3. Withhold water for about 1–2 hours in the early morning so the birds are thirsty. In winter, birds drink slowly, so do not stretch this beyond 2 hours for young chicks under brooders.
  4. Add skim milk powder (commonly about 2 g per litre) or a vaccine stabiliser as per its label, and stir it into the water 15–20 minutes before the vaccine. It protects the virus from any traces of chlorine.
  5. Open the vial under the water, mix well, and use it at once. Use clean, cool water; never add hot water to make it “comfortable”.
  6. Give only as much water as the birds will finish in 1.5–2 hours. In winter this is usually less than you think, so measure yesterday’s morning intake.
  7. Make sure there are enough drinkers so all birds can drink at the same time. Raise the brooder heat slightly so birds are not too cold to walk to the water.
  8. After the vaccine water is finished, give the next water of the schedule (on day 4: Alceau). Never put vitamins, herbal products, antibiotics or anything else in the vaccine water.

Eye or nose drop

Put one drop in one eye or nostril, and hold the chick until the drop is taken in. Use the dropper and diluent that come with the vaccine, and keep the mixed vaccine cool and in the shade while you work.

Coccidiosis prevention: check your feed bag first

  • Most commercial broiler feeds in India already contain a coccidiostat. Read the feed bag label or ask your feed supplier which one and at what level.
  • Do not add another anticoccidial in water “for safety” while the feed already has one. Double dosing can harm the birds and adds residue risk. Give a water anticoccidial only when your vet confirms coccidiosis.
  • Some coccidiostats (ionophores) react badly with certain antibiotics such as tiamulin. Always tell your vet which feed you are using before any treatment.
  • In winter, coccidiosis follows wet litter. Fix leaking drinkers and damp patches early: see wet litter and loose droppings in winter.

Antibiotics: not in the schedule, only on diagnosis

Many printed “42 days schedules” include antibiotics on fixed days. The IMN winter schedule does not, and we do not recommend it.

  • Antibiotics do not kill viruses. They do nothing against ND, IB or Gumboro themselves.
  • Routine use breeds resistant bacteria, so when you really need a medicine it may not work.
  • Use an antibiotic only when your vet diagnoses a bacterial problem (for example E. coli or CRD), ideally after a post-mortem, at the correct dose and for the full course.
  • Respect the withdrawal period written on the label before sale. Meat with residues is unsafe for consumers and bad for your name with buyers.
  • Colistin is banned in India for food-producing animals and poultry. Do not buy it, even if it is offered.
  • Write every product, medicine, dose, day and withdrawal period in your farm register.

Winter disease watch-list

A schedule supports the flock; it does not replace your eyes. Walk the shed every morning and again at night, when the birds are quiet and breathing sounds are easy to hear. Rough guide only; a vet and post-mortem confirm the cause.

DiseaseSigns to watchWhat to do
CRD (Mycoplasma)Rattling at night, sneezing, foamy eyes, slow growth; often after vaccine stress or high ammoniaImprove fresh air, cut ammonia, call vet; antibiotic only if prescribed
E. coli (colibacillosis)Dull, fluffed birds, rising deaths; at post-mortem cloudy air sacs, white layer on heart and liverPost-mortem and vet; clean water lines; treatment as prescribed, keep withdrawal
Infectious bronchitis (IB)Whole shed sneezing within 1–2 days, gasping, wet eyes; kidney form: wet droppings with lots of white uratesVet, warmth without closing the shed fully, immunity and kidney support
Ranikhet / NDGreen watery droppings, twisted neck, paralysis, sharply rising deathsCall vet the same day; strict biosecurity; follow vet’s emergency plan
Ascites / SDSSwollen, fluid-filled belly, bluish comb, hard breathing; heavy birds dead on their backMore fresh air, avoid chilling, Ascitox Q10 control dose with vet’s advice
Gout / kidney troubleChalky white urates, dull birds, low water intakeCheck water intake, call vet
Coccidiosis (wet litter)Bloody, orange or mucous droppings, huddled birds, poor feed intakeVet confirmation, fix wet litter, anticoccidial only if diagnosed, no double dosing

If an outbreak is diagnosed, do not change the schedule on your own. Send the details on WhatsApp so the team can tell you what to pause and what to continue alongside your vet’s treatment.

Water medication rules in cold weather

In winter, broilers drink less than in summer. If you mix a product for the “book” water intake, the birds may not drink the full dose. Follow these rules:

  • First water in the morning, when birds are active and drinking. Give the next water only when the first one is finished.
  • Measure actual intake. Note how many litres the flock drank yesterday, and how much of it in the first 3–4 hours after lights on.
  • Dissolve the day’s quantity in the water they will really drink in 3–4 hours. Example: 1,000 birds drank 120 litres yesterday, about 40 litres of it in the first 3–4 hours. The day’s product goes into those 40 litres, not into 120 litres.
  • Stir well, and check that the product dissolves. Undissolved powder settles in tanks and blocks nipples.
  • Combine products only where the schedule joins them with “+”. Do not add your own extras.
  • Keep plain-water days plain.
  • Flush water lines after each product and before vaccination.

Printable shed checklist

  • Schedule chart pinned in the shed; each day ticked off after giving
  • Quantities multiplied for your bird count (chart is per 1,000 birds)
  • Hatchery vaccine details written in the register
  • Day 4 ND-IB: vaccine water only, Alceau in the next water
  • Gumboro and LaSota days fixed with your vet and marked on the wall calendar
  • Vaccines carried in an ice box; chlorine stopped the day before each vaccine
  • Skim milk or stabiliser ready; vaccine water finished within 1.5–2 hours
  • Plain-water days 23, 31, 35, 37, 39, 40 kept plain
  • Feed bag label checked for coccidiostat; no extra anticoccidial without vet
  • No antibiotic without a vet’s diagnosis; withdrawal period noted
  • Daily water intake and deaths written down
  • Weekly weight on day 7, 14, 21, 28, 35

Keep your costs in view too: our poultry cost and profit calculator shows how medicine spend and mortality change your margin.

Common mistakes with a winter medicine schedule

  1. Mixing a product into vaccine water. Vaccine water has only the vaccine plus skim milk or stabiliser.
  2. Not scaling the quantity. The chart is per 1,000 birds; 4,000 birds need 4 times the quantity.
  3. Dissolving in a full day’s water. The birds get only part of the dose. Use the water they finish in 3–4 hours.
  4. Giving the next water before the first is finished, or mixing both entries in one tank.
  5. Skipping plain-water days to “add something extra”. They are rest days for the gut and kidneys.
  6. Antibiotics on fixed days “for prevention”. Wasted money, resistance and residues.
  7. Double anticoccidial: one in feed, another in water.
  8. Closing the shed fully at night. Ammonia and low oxygen bring CRD, E. coli and ascites, and no product fixes bad air.
  9. Selling birds before a vet-prescribed medicine’s withdrawal period is over.

Frequently asked questions

Is this schedule for 1,000 birds only?

The quantities are per 1,000 birds. Multiply for your flock: 3,000 birds = 3 times, 10,000 birds = 10 times.

What is the total cost?

About ₹4,860 per 1,000 birds for 42 days, about ₹4.9 per chick. The ND-IB vaccine and any other vaccines your vet adds are extra.

My hatchery already gave ND+IB. Do I still vaccinate on day 4?

Day 4 is the day the IMN schedule sets for ND-IB. If your hatchery already gave ND+IB, ask your vet whether to keep or shift it.

Can I add a product to the vaccine water to “prevent reaction”?

No. Nothing goes in vaccine water except skim milk or stabiliser. Give the schedule’s next water after the vaccine water is finished. A mild sneeze after IB or ND vaccine is usually a normal reaction that settles in a few days with good ventilation. If deaths rise, call your vet.

What do I do on the Gumboro or LaSota day?

Vaccine water first, alone. Then give that day’s schedule products in the next water. Ask on WhatsApp if you are unsure.

Why are some days plain water?

Day 23, 31, 35, 37, 39 and 40 are rest days for the gut and kidneys. Give clean drinking water only.

My feed has a coccidiostat. Do I still need a coccidiosis medicine?

Not as routine. Keep the litter dry and watch droppings. If you see bloody or mucous droppings and dull birds, call your vet; a water treatment is given only on diagnosis.

Can I use this schedule in an open shed?

It is made for EC farmers. If you run an open-sided shed, ask the team on WhatsApp before you start.

Questions about the schedule? Send your bird count, age, hatchery vaccine details and any problem on WhatsApp +91 98715 84101. Dr. Ibne Ali’s team will help you fit the schedule and vaccine days to your farm. Ask on WhatsApp

Also read: winter management in poultry farming · infectious bronchitis in poultry · wet litter in winter · aaj ka broiler rate · IMN poultry products

Scroll to Top