The majority of antibodies during a primary immune response are of the class IgM. Primary immune response means first ever encounter with antigen. When the same antigen strikes again IgY or IgA become more apparent.
Cause of vaccination failures – During IBD (gumboro) infection, virus mainly targets IgM bearing lymphocytes therefore IBD interfere with primary immune response
IgM has the ability to easily agglutinate large antigens and to cause the precipitation of soluble antigens, thus greatly enhancing the immune system’s ability to remove antigens through phagocytosis. IgA is found in secretions and functions at mucosal surfaces & contribute mucosal immunity, and IgY can be transferred from the peripheral circulation of the hen into the egg (maternal antibody).
Under natural conditions, the serum IgY of laying hens is deposited in large quantities in the egg yolk in order to protect the developing embryo from potential pathogens. Oral administration of specific IgY antibody has been shown to be effective against a variety of intestinal pathogens.
Viral Outbreaks in Poultry and Their Management
Herbal products against viral outbreaks – An Investigation
Why antibiotics do increases mortality in viral outbreaks?
Immunology of Poultry Birds – Basics of Avian Immunology
Practical use of knowledge of the avian immune system
Ethnoveterinary Medicine (EVM) and Viral Challenges in Poultry – Lessons from Field
Phytobiotics as strategic antiviral compounds – an advanced herbal science
Warning
Do not go for every herbal-labelled product that claims successful treatment
This is just an example that how we can explore potential antiviral herbs. During the above exploration, I came across many surprisingly unique points of avian immunology along with herbs and molecules that could effectively regulate it. With the help of the above information, I designed a product named VIROCON a few years back which controls mortalities in severe viral outbreaks. I mean it is really possible to save birds sometimes through knowledge of immunology and special intervention in the light of scientific evidence.
Note: above-quoted information is my own opinion backed by proven research and available scientific knowledge. Viral diseases in poultry is a non-ending subject in which research is going on and according to some experts, we do not even know 50% of all the diseases affecting poultry. New emerging viral diseases and modifications in existing strains make it more difficult to treat and control viral outbreaks by poultry health service providers. This is not the end of the document, I am exploring new things and adding to this document in future, INSHALLAH.
Dr Ibne Ali running ‘Ali Veterinary Wisdom’ with the sole purpose of educating poultry and livestock farmers. We try to help farmers by advising them during disease outbreaks, regarding the prevention of viral diseases, biosecurity planning, feed formulation, toxicity management and farm auditing.